Blausen Medical
Blausen Medical

Blausen Medical

Medically accurate and informative 3D animations


MagnICON Transient Gene Expression

The Icon Genetics magnICON technology is a state-of-the-art, virus-based transient expression system to produce recombinant proteins in plants. Agrobacteria serve as mediators for transport of a special DNA fragment, the T-DNA, to the plant cells. The T-DNA harbors the virus-based DNA with the Gene-of-interest. A Single-strand T-DNA copy is delivered to the plant nucleus. There, the virus-based DNA with the Gene-of-Interest is transcribed to a plant-viral RNA, the plant-viral RNA is transported to the cytoplasm, highly replicated and then translated by ribosomes to create the Protein-of-Interest in amounts up to the biological limit. The Protein-of-Interest can undergo further posttranslational folding and processing required for its proper function in the final protein product. With the magnICON technology from Icon Genetics, large quantities of these proteins can be created with unprecedented safety, speed, and scalability.

Duration: 01:21
Licence: CC - Attribution
Original Language: English
Published: 2/9/2023

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MagnICON Transient Gene Expression

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